The Buddha describes the three defilements - the taint of sensual desire, the taint of being, and the taint of ignorance, and the way of practice leading to their cessation.

Paṭhamaāsava sutta - Defilements (First)

This was said by the Blessed One, said by the Arahant, so I have heard:

"Bhikkhus, there are these three defilements. What three? The taint of sensual desire, the taint of being, and the taint of ignorance. These are the three defilements."

The Blessed One spoke on this matter. In this regard, it is said:

"Collected, fully aware, a mindful disciple of the Buddha; Discerns the defilements, and the arising of defilements.
Where these cease, and the way of practice leading to their cessation; With the cessation of defilements, the bhikkhu, is satiated and completely quenched [of mental defilements]."

This matter too was spoken by the Blessed One, as I have heard.