One is incapable of ending suffering without directly knowing and fully understanding the five aggregates, without becoming dispassionate towards them and without abandoning them.
Abhijāna sutta - Directly Knowing
At Sāvatthi.
"Bhikkhus, without directly knowing and without fully understanding form, without becoming dispassionate towards it and without abandoning it, one is incapable of achieving the complete ending of suffering;
without directly knowing and without fully understanding sensation, without becoming dispassionate towards it and without abandoning it, one is incapable of achieving the complete ending of suffering;
without directly knowing and without fully understanding perception, without becoming dispassionate towards it and without abandoning it, one is incapable of achieving the complete ending of suffering;
without directly knowing and without fully understanding volitional formations, without becoming dispassionate towards it and without abandoning it, one is incapable of achieving the complete ending of suffering;
without directly knowing and without fully understanding consciousness, without becoming dispassionate towards it and without abandoning it, one is incapable of achieving.
Indeed, bhikkhus, by directly knowing, by fully understanding form, by becoming dispassionate towards it, and by abandoning it, one is capable of achieving the complete ending of suffering;
by directly knowing, by fully understanding sensation, by becoming dispassionate towards it, and by abandoning it, one is capable of achieving the complete ending of suffering;
by directly knowing, by fully understanding perception, by becoming dispassionate towards it, and by abandoning it, one is capable of achieving the complete ending of suffering;
by directly knowing, by fully understanding volitional formations, by becoming dispassionate towards it, and by abandoning it, one is capable of achieving
by directly knowing, by fully understanding consciousness, by becoming dispassionate towards it, and by abandoning it, one is capable of achieving the complete ending of suffering.